FOXA2 antibody (Middle Region)

Catalog No. ABIN952361

The Rabbit Polyclonal anti-FOXA2 antibody has been validated for WB, IF, IHC (p) and EIA. It is suitable to detect FOXA2 in samples from Human.

Quick Overview for FOXA2 antibody (Middle Region) (ABIN952361)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FOXA2 Antibody

Binding Specificity: AA 135-164, Middle Region

Specificity: This antibody recognizes Human FOXA2 / HNF3B (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human FOXA2 / HNF3B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: FOXA2 / HNF3B

Background: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.Synonyms: HNF-3-beta, HNF-3B, Hepatocyte nuclear factor 3-beta, TCF3B, Transcription factor 3B

Molecular Weight: 48306 Da

Gene ID: 3170

NCBI Accession: NP_068556

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process