Fukutin antibody (Middle Region)

Catalog No. ABIN952403

The Rabbit Polyclonal anti-Fukutin antibody is suitable to detect Fukutin in samples from Human and Mouse. It has been validated for WB, IHC (p) and EIA.

Quick Overview for Fukutin antibody (Middle Region) (ABIN952403)

Target: Fukutin (FKTN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Fukutin Antibody

Binding Specificity: AA 184-214, Middle Region

Specificity: This antibody recognizes Human and Mouse FKTN (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 184-214 amino acids from the Central region of Human Fukutin. Genename: FKTN

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: Fukutin

Background: The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.Synonyms: FCMD, FKTN, Fukuyama-type congenital muscular dystrophy protein

Molecular Weight: 53724 Da

Gene ID: 2218

NCBI Accession: NP_001073270

Pathways: Regulation of Carbohydrate Metabolic Process