GBE1 antibody (Middle Region)

Catalog No. ABIN952469

The Rabbit Polyclonal anti-GBE1 antibody has been validated for WB, IF and EIA. It is suitable to detect GBE1 in samples from Human and Mouse.

Quick Overview for GBE1 antibody (Middle Region) (ABIN952469)

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-GBE1 Antibody

Binding Specificity: AA 534-564, Middle Region

Specificity: This antibody recognizes Human and Mouse GBE1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 534~564 amino acids from the Central region of human GBE1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GBE1

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Alternative Name: GBE1

Background: GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease.Synonyms: 1, 4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme

Molecular Weight: 80460 Da

Gene ID: 2632

NCBI Accession: NP_000149

Pathways: Cellular Glucan Metabolic Process