GGTLC2 antibody (Middle Region)

Catalog No. ABIN952511

The Rabbit Polyclonal anti-GGTLC2 antibody has been validated for WB, FACS, IHC (p) and EIA. It is suitable to detect GGTLC2 in samples from Human.

Quick Overview for GGTLC2 antibody (Middle Region) (ABIN952511)

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGTLC2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-GGTLC2 Antibody

Binding Specificity: AA 140-169, Middle Region

Specificity: This antibody recognizes Human GGTLC2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human GGTLC2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GGTLC2

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Alternative Name: GGTLC2

Background: Gamma-glutamyltransferase-1 (GGT1, MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].Synonyms: GGTL4, Gamma-glutamyltransferase light chain 2

Molecular Weight: 23661 Da

Gene ID: 91227

NCBI Accession: NP_954578