Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GUCY2D antibody (Middle Region)

GUCY2D Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952663
  • Target See all GUCY2D Antibodies
    GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 1
    AA 547-578, Middle Region
    Reactivity
    • 23
    • 2
    • 1
    Human
    Host
    • 19
    • 4
    Rabbit
    Clonality
    • 20
    • 3
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    This GUCY2D antibody is un-conjugated
    Application
    • 20
    • 20
    • 12
    • 12
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human GUCY2D / RETGC1 (Center).
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 547-578 amino acids from the Central region of human GUCY2D / RETGC1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GUCY2D Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
    Alternative Name
    GUCY2D / RETGC1 (GUCY2D Products)
    Synonyms
    GUCY2D antibody, CORD5 antibody, CORD6 antibody, CYGD antibody, GUC1A4 antibody, GUC2D antibody, LCA antibody, LCA1 antibody, RCD2 antibody, RETGC-1 antibody, ROS-GC1 antibody, ROSGC antibody, retGC antibody, guanylate cyclase 2D, retinal antibody, guanylate cyclase 2d antibody, GUCY2D antibody, Gucy2d antibody
    Background
    This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].Synonyms: CORD6, GUC1A4, GUC2D, PGCD, RETGC, RETGC-1, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase, retinal Guanylate cyclase 2D
    Molecular Weight
    120059 Da
    Gene ID
    3000
    NCBI Accession
    NP_000171
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
You are here:
Support