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GUCY2D antibody (Middle Region)
GUCY2D
Reactivity: Human
WB, FACS, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GUCY2D Antibody
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Target
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GUCY2D
(Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
Binding Specificity
All epitopes for GUCY2D antibodies
AA 547-578, Middle Region
Reactivity
All reactivities for GUCY2D antibodies
Human
Host
All hosts for GUCY2D antibodies
Rabbit
Clonality
All clonalities for GUCY2D antibodies
Polyclonal
Conjugate
All conjugates for GUCY2D antibodies
This GUCY2D antibody is un-conjugated
Application
All applications for GUCY2D antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human GUCY2D / RETGC1 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 547-578 amino acids from the Central region of human GUCY2D / RETGC1
Isotype
Ig Fraction
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Discover our top product GUCY2D Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for GUCY2D
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Target
GUCY2D
(Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
Alternative Name
GUCY2D / RETGC1 (GUCY2D Products )
Synonyms
GUCY2D antibody, CORD5 antibody, CORD6 antibody, CYGD antibody, GUC1A4 antibody, GUC2D antibody, LCA antibody, LCA1 antibody, RCD2 antibody, RETGC-1 antibody, ROS-GC1 antibody, ROSGC antibody, retGC antibody, guanylate cyclase 2D, retinal antibody, guanylate cyclase 2d antibody, GUCY2D antibody, Gucy2d antibody
Background
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].Synonyms: CORD6, GUC1A4, GUC2D, PGCD, RETGC, RETGC-1, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase, retinal Guanylate cyclase 2D
Molecular Weight
120059 Da
Gene ID
3000
NCBI Accession
NP_000171
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Phototransduction
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