HAUS3 antibody (HAUS Augmin-Like Complex, Subunit 3) (AA 379-408)

Details for Product anti-HAUS3 Antibody No. ABIN952682
Antigen
  • C4orf15
  • IT1
  • dgt3
  • D4S43h
  • D5H4S43
  • D5H4S43E
  • HAUS augmin like complex subunit 3
  • HAUS augmin-like complex, subunit 3
  • HAUS3
  • Haus3
Epitope
AA 379-408, Middle Region
9
7
7
7
2
1
1
1
1
Reactivity
Human
45
21
20
3
2
1
1
1
Host
Rabbit
45
Clonality
Polyclonal
Conjugate
This HAUS3 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
21
19
13
5
Options
Immunogen KLH conjugated synthetic peptide between 379-408 amino acids from the Central region of human HAUS3
Isotype Ig Fraction
Specificity This antibody recognizes Human HAUS3 (Center).
Purification Protein A column, followed by peptide affinity purification
Plasmids, Primers & others Plasmids, Primers & others HAUS3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name HAUS3 (HAUS3 Antibody Abstract)
Background HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220], Uehara et al., 2009 [PubMed 19369198]).Synonyms: C4orf15, HAUS augmin-like complex subunit 3
Molecular Weight 69650 Da
Gene ID 79441
NCBI Accession NP_078787
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-HAUS Augmin-Like Complex, Subunit 3 (HAUS3) (AA 379-408), (Middle Region) antibody (ABIN952682) Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis ti...
Image no. 2 for anti-HAUS Augmin-Like Complex, Subunit 3 (HAUS3) (AA 379-408), (Middle Region) antibody (ABIN952682) Western blot analysis of HAUS3 Antibody (Center) in ZR-75-1 cell line lysates (35ug/l...
Background publications Shah, Morin, Khattra, Prentice, Pugh, Burleigh, Delaney, Gelmon, Guliany, Senz, Steidl, Holt, Jones, Sun, Leung, Moore, Severson, Taylor, Teschendorff, Tse, Turashvili, Varhol, Warren, Watson, Zhao, Caldas, Huntsman, Hirst, Marra, Aparicio: "Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution." in: Nature, Vol. 461, Issue 7265, pp. 809-13, 2009 (PubMed).

Lawo, Bashkurov, Mullin, Ferreria, Kittler, Habermann, Tagliaferro, Poser, Hutchins, Hegemann, Pinchev, Buchholz, Peters, Hyman, Gingras, Pelletier: "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity." in: Current biology : CB, Vol. 19, Issue 10, pp. 816-26, 2009 (PubMed).

Uehara, Nozawa, Tomioka, Petry, Vale, Obuse, Goshima: "The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 17, pp. 6998-7003, 2009 (PubMed).

Goshima, Mayer, Zhang, Stuurman, Vale: "Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle." in: The Journal of cell biology, Vol. 181, Issue 3, pp. 421-9, 2008 (PubMed).

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