HMGB3 antibody (Middle Region)

Catalog No. ABIN952762

This Rabbit Polyclonal antibody specifically detects HMGB3 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for HMGB3 antibody (Middle Region) (ABIN952762)

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HMGB3 Antibody

Binding Specificity: AA 49-79, Middle Region

Specificity: This antibody recognizes Human HMGB3 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 49-79 amino acids from the Central region of human HMGB3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HMGB3

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Alternative Name: HMGB3

Background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291], Nemeth et al., 2006 [PubMed 16945912]).Synonyms: HMG-2a, HMG-4, HMG2A, HMG4, HMGB-3, High mobility group protein 2a, High mobility group protein 4, High mobility group protein B3

Molecular Weight: 22980 Da

Gene ID: 3149

NCBI Accession: NP_005333