HOXB3 antibody (Middle Region)

Catalog No. ABIN952777

This Rabbit Polyclonal antibody specifically detects HOXB3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for HOXB3 antibody (Middle Region) (ABIN952777)

Target: HOXB3 (Homeobox B3 (HOXB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HOXB3 Antibody

Binding Specificity: AA 118-148, Middle Region

Specificity: This antibody recognizes Human HOXB3 / HOX2G (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 118-148 amino acids from the Central region of Human HOXB3 / HOX2G

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HOXB3

Target: HOXB3 (Homeobox B3 (HOXB3))

Alternative Name: HOXB3 / HOX2G

Background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).Synonyms: Homeobox protein Hox-B3, Hox-2.7, Hox-2G

Molecular Weight: 44340 Da

Gene ID: 3213

NCBI Accession: NP_002137