HOXB6 antibody (Middle Region)

Catalog No. ABIN952778

Product Details anti-HOXB6 Antibody

Target: HOXB6 (Homeobox B6 (HOXB6))

Binding Specificity: AA 135-163, Middle Region

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse HOXB6 / HOX2B (Center). Other species not tested.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human HOXB6 / HOX2B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HOXB6

Target: HOXB6 (Homeobox B6 (HOXB6))

Alternative Name: HOXB6 / HOX2B (HOXB6 Products)

Background: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.Synonyms: HU-2, Homeobox protein Hox-B6, Hox-2.2, Hox-2B

Molecular Weight: 25432 Da

Gene ID: 3216

NCBI Accession: NP_061825