HOXB6 antibody (Middle Region)

Catalog No. ABIN952778

The Rabbit Polyclonal anti-HOXB6 antibody is suitable to detect HOXB6 in samples from Mouse and Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for HOXB6 antibody (Middle Region) (ABIN952778)

Target: HOXB6 (Homeobox B6 (HOXB6))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HOXB6 Antibody

Binding Specificity: AA 135-163, Middle Region

Specificity: This antibody recognizes Human and Mouse HOXB6 / HOX2B (Center). Other species not tested.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human HOXB6 / HOX2B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HOXB6

Target: HOXB6 (Homeobox B6 (HOXB6))

Alternative Name: HOXB6 / HOX2B

Background: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.Synonyms: HU-2, Homeobox protein Hox-B6, Hox-2.2, Hox-2B

Molecular Weight: 25432 Da

Gene ID: 3216

NCBI Accession: NP_061825