KDM4B antibody (N-Term)

Catalog No. ABIN952973

There is 1 publication for this product available. The Rabbit Polyclonal anti-KDM4B antibody is suitable to detect KDM4B in samples from Human. It has been validated for WB, FACS, IHC (p) and EIA.

Quick Overview for KDM4B antibody (N-Term) (ABIN952973)

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-KDM4B Antibody

Binding Specificity: AA 10-40, N-Term

Specificity: This antibody recognizes Human JMJD2B / KDM4B (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 10~40 amino acids from the N-terminal region of human JMJD2B Genename: KDM4B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-KDM4B antibody (ABIN952973)

Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

Target Details for KDM4B

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Alternative Name: JMJD2B / KDM4B

Background: KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36Synonyms: JHDM3B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KIAA0876, Lysine-specific demethylase 4B

Molecular Weight: 121897 Da

Gene ID: 23030

NCBI Accession: NP_055830

Pathways: Warburg Effect