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KDM4B antibody (N-Term)

The Rabbit Polyclonal anti-KDM4B antibody has been validated for WB, FACS, IHC (p) and EIA. It is suitable to detect KDM4B in samples from Human. There is 1 publication available.
Catalog No. ABIN952973

Quick Overview for KDM4B antibody (N-Term) (ABIN952973)

Target

See all KDM4B Antibodies
KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This KDM4B antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    AA 10-40, N-Term

    Specificity

    This antibody recognizes Human JMJD2B / KDM4B (N-term).

    Purification

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 10~40 amino acids from the N-terminal region of human JMJD2B Genename: KDM4B

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

  • Target

    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

    Alternative Name

    JMJD2B / KDM4B

    Background

    KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36Synonyms: JHDM3B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KIAA0876, Lysine-specific demethylase 4B

    Molecular Weight

    121897 Da

    Gene ID

    23030

    NCBI Accession

    NP_055830

    Pathways

    Warburg Effect
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