KDM4C antibody (C-Term)

Catalog No. ABIN952976

The Rabbit Polyclonal anti-KDM4C antibody has been validated for WB, FACS and EIA. It is suitable to detect KDM4C in samples from Human.

Quick Overview for KDM4C antibody (C-Term) (ABIN952976)

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-KDM4C Antibody

Binding Specificity: AA 1030-1056, C-Term

Specificity: This antibody recognizes Human JMJD2C / KDM4C (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C Genename: KDM4C

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: JMJD2C / KDM4C

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.Synonyms: GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KIAA0780, Lysine-specific demethylase 4C

Molecular Weight: 119982 Da

Gene ID: 23081

NCBI Accession: NP_001140166

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect