MXD3 antibody (N-Term)

Catalog No. ABIN953278

This Rabbit Polyclonal antibody specifically detects MXD3 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for MXD3 antibody (N-Term) (ABIN953278)

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MXD3 Antibody

Binding Specificity: AA 27-56, N-Term

Specificity: This antibody recognizes human MAD3 at N-term.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 27-56aa) of human MAD3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Alternative Name: MAD3

Background: The MXD3 gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The Max-associated protein 3 / MAD3 forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.Synonyms: MAD-3, MXD3, Max-interacting transcriptional repressor MAD3

Molecular Weight: 23477 Da

Gene ID: 83463

NCBI Accession: NP_001136407