Myeloperoxidase antibody (N-Term)
Quick Overview for Myeloperoxidase antibody (N-Term) (ABIN953571)
Target
See all Myeloperoxidase (MPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 66-97, N-Term
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Specificity
- This antibody recognizes human Myeloperoxidase at N-term.
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 66-97aa) of human Myeloperoxidase
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Myeloperoxidase (MPO)
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Alternative Name
- Myeloperoxidase
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Background
- Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.Synonyms: MPO
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Molecular Weight
- 83869 Da
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Gene ID
- 4353
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NCBI Accession
- NP_000241
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Pathways
- Chromatin Binding
Target
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