PDE7B antibody (C-Term)

Catalog No. ABIN954068

The Rabbit Polyclonal anti-PDE7B antibody has been validated for WB and EIA. It is suitable to detect PDE7B in samples from Human.

Quick Overview for PDE7B antibody (C-Term) (ABIN954068)

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PDE7B Antibody

Binding Specificity: AA 424-454, C-Term

Specificity: This antibody recognizes Human PDE7B (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 424-454 amino acids from the C-terminal region of Human PDE7B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PDE7B

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Alternative Name: PDE7B

Background: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.Synonyms: 5'-cyclic phosphodiesterase 7B, MGC88256, Phosphodiesterase 7B, cAMP-specific 3', rolipram-insensitive phosphodiesterase type 7

Molecular Weight: 51835 Da

Gene ID: 27115

NCBI Accession: NP_061818

Pathways: cAMP Metabolic Process