Full-length recombinant Peripherin protein. Production: After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
2.0 mg IgY/ml
Buffer
10 mM PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted in the dark at 2-8 °C.
Target
Peripherin (PRPH)
Alternative Name
Peripherin
Background
Human Perpherin is a 53,651 dalton protein (470 amino acids) expressed in all PNS neurons and some CNS neurons, including a subset of cortical neurons, hippocampal neurons, and ventral horn spinal cord motor neurons. At an ultrastructural level, peripherin immunoreactivity is associated with the neurofilament portion of the cytoskeleton, being particularly abundant in the cell body. Peripherin protein has been shown to undergo upregulation during periods of trophic stress in cultured neurons, and mutations of the peripherin gene have been associated with the neurodegenerative disease amyotrophic lateral sclerosis.Synonyms: NEF4, PRPH, PRPH1