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Phosducin antibody (Middle Region)

This Rabbit Polyclonal antibody specifically detects Phosducin in WB and EIA. It exhibits reactivity toward Human.
Catalog No. ABIN954124

Quick Overview for Phosducin antibody (Middle Region) (ABIN954124)

Target

See all Phosducin (PDC) Antibodies
Phosducin (PDC)

Reactivity

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 12
  • 1
Rabbit

Clonality

  • 13
Polyclonal

Conjugate

  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
This Phosducin antibody is un-conjugated

Application

  • 13
  • 7
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-89, Middle Region

    Specificity

    This antibody recognizes Human Phosducin / PDC (Center).

    Purification

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 58-89 amino acids from the Central region of Human Phosducin / PDC.

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Phosducin (PDC)

    Alternative Name

    Phosducin / PDC

    Background

    This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: 33 kDa phototransducing protein, MEKA, PHD, PhLOP

    Molecular Weight

    28246 Da

    Gene ID

    5132

    NCBI Accession

    NP_002588
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