Phospholipase C delta 3 antibody (N-Term)

Catalog No. ABIN954186

This anti-Phospholipase C delta 3 antibody is a Rabbit Polyclonal antibody detecting Phospholipase C delta 3 in WB and EIA. Suitable for Human and Mouse.

Quick Overview for Phospholipase C delta 3 antibody (N-Term) (ABIN954186)

Target: Phospholipase C delta 3 (PLCd3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C delta 3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Phospholipase C delta 3 Antibody

Binding Specificity: AA 59-89, N-Term

Specificity: This antibody recognizes Human and Mouse PLCD3 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 59-89 amino acids from the N-terminal region of human PLCD3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Alternative Name: PLCD3

Background: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq].Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-3, PLC-delta-3, Phospholipase C delta 3, Phospholipase C-delta-3

Molecular Weight: 89258 Da

Gene ID: 113026

NCBI Accession: NP_588614

Pathways: WNT Signaling