PON2 antibody (N-Term)

Catalog No. ABIN954246

The Rabbit Polyclonal anti-PON2 antibody (ABIN954246) specifically detects PON2 in WB, FACS, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for PON2 antibody (N-Term) (ABIN954246)

Target: PON2 (Paraoxonase 2 (PON2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PON2 Antibody

Binding Specificity: AA 78-107, N-Term

Specificity: This antibody recognizes Human PON2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of human PON2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: PON2

Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.Synonyms: A-esterase 2, Aromatic esterase 2, PON 2, PON-2, Serum aryldialkylphosphatase 2, Serum paraoxonase/arylesterase 2

Molecular Weight: 39398 Da

Gene ID: 5445

NCBI Accession: NP_000296