RPGR antibody (C-Term)

Catalog No. ABIN954582

The Rabbit Polyclonal anti-RPGR antibody (ABIN954582) specifically detects RPGR in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for RPGR antibody (C-Term) (ABIN954582)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RPGR Antibody

Binding Specificity: AA 743-772, C-Term

Specificity: This antibody reacts to RPGR.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 743-772 amino acids from the C-terminal region of human RPGR

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR

Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.Synonyms: RP3, X-linked retinitis pigmentosa GTPase regulator, XLRP3

Molecular Weight: 113387 Da

Gene ID: 6103

NCBI Accession: NP_000319