SCP2 antibody (N-Term)

Catalog No. ABIN954693

Product Details anti-SCP2 Antibody

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Binding Specificity: AA 13-43, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SCP2 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of Human SCP2 Genename: SCP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Alternative Name: SCP2 / SCPX (SCP2 Products)

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.Synonyms: NSL-TP, Non-specific lipid-transfer protein, Propanoyl-CoA C-acyltransferase, SCP-2, SCP-X, SCP-chi, Sterol carrier protein 2, Sterol carrier protein X

Gene ID: 6342

NCBI Accession: NP_001007100

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process