Septin 2 antibody (C-Term)
Quick Overview for Septin 2 antibody (C-Term) (ABIN954726)
Target
See all Septin 2 (SEPT2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 279-309, C-Term
-
Specificity
- Recognizes SEPT2 (C-term).
-
Purification
- Protein A column followed by peptide Affinity purification
-
Immunogen
- KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Septin 2 (SEPT2)
-
Alternative Name
- Septin-2
-
Background
- Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Synonyms: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT-2, SEPT2, Septin2
-
Gene ID
- 4735
-
NCBI Accession
- NP_001008491
Target
-