SH2D4A antibody (N-Term)

Catalog No. ABIN954787

This Rabbit Polyclonal antibody specifically detects SH2D4A in WB, IHC (p) and EIA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for SH2D4A antibody (N-Term) (ABIN954787)

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SH2D4A Antibody

Binding Specificity: AA 45-75, N-Term

Specificity: Recognizes SH2D4A (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 45-75 amino acids from the N-terminal region of Human SH2D4A Genename: SH2D4A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-SH2D4A antibody (ABIN954787)

Lapinski, Oliver, Kamen, Hughes, Saunders, King: "Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 2019-27, (2008) (PubMed).

Target Details for SH2D4A

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Alternative Name: SH2D4A

Background: SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.Synonyms: Protein SH(2)A, SH2 domain-containing protein 4A, SH2A

Gene ID: 63898

NCBI Accession: NP_001167630