SH3PXD2A antibody (N-Term)

Catalog No. ABIN954793

Product Details anti-SH3PXD2A Antibody

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Binding Specificity: AA 221-250, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3PXD2A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Recognizes SH3PXD2A (N-term) .

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 221-250 amino acids from the N-terminal region of Human SH3PXD2A Genename: SH3PXD2A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Target Details for SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Alternative Name: SH3PXD2A (SH3PXD2A Products)

Background: SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.Synonyms: Adaptor protein TKS5, FISH, Five SH3 domain-containing protein, KIAA0418, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, SH3MD1, TKS5

Molecular Weight: 125289 Da

Gene ID: 9644

NCBI Accession: NP_055446