SLCO1B1 antibody (Middle Region)

Catalog No. ABIN954831

The Rabbit Polyclonal anti-SLCO1B1 antibody (ABIN954831) specifically detects SLCO1B1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for SLCO1B1 antibody (Middle Region) (ABIN954831)

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLCO1B1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SLCO1B1 Antibody

Binding Specificity: AA 273-302, Middle Region

Specificity: This antibody recognizes Human SLCO1B1 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 273~302 amino acids from the Central region of Human SLCO1B1 Genename: SLCO1B1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLCO1B1

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Alternative Name: SLCO1B1 / OATP2

Background: SLCO1B1 is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.Synonyms: LST-1, LST1, Liver-specific organic anion transporter 1, OATP-2, OATP-C, OATPC, SLC21A6, Sodium-independent organic anion-transporting polypeptide 2, Solute carrier family 21 member 6, Solute carrier organic anion transporter family member 1B1

Molecular Weight: 76449 Da

Gene ID: 10599

NCBI Accession: NP_006437