Snurportin 1 antibody (Middle Region)

Catalog No. ABIN954877

This Rabbit Polyclonal antibody specifically detects Snurportin 1 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Snurportin 1 antibody (Middle Region) (ABIN954877)

Target: Snurportin 1 (SNUPN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Snurportin 1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Snurportin 1 Antibody

Binding Specificity: AA 199-228, Middle Region

Specificity: This antibody detects Snurportin-1 (SNUPN).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region ( between 199-228aa) of human Snurportin-1 (SNUPN).

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Snurportin 1

Target: Snurportin 1 (SNUPN)

Alternative Name: Snurportin-1 (SNUPN)

Background: The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.Synonyms: KPNBL, RNA U transporter 1, RNUT1, SPN1, Snurportin1

Gene ID: 10073

NCBI Accession: NP_001036046

Pathways: Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus