SORD antibody (Middle Region)

Catalog No. ABIN954884

The Rabbit Polyclonal anti-SORD antibody has been validated for WB and EIA. It is suitable to detect SORD in samples from Human.

Quick Overview for SORD antibody (Middle Region) (ABIN954884)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SORD Antibody

Binding Specificity: AA 210-239, Middle Region

Specificity: This antibody recognizes Human SORD (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of Human SORD. Genename: SORD

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. Synonyms: L-iditol 2-dehydrogenase, Sorbitol dehydrogenase

Molecular Weight: 38325 Da

Gene ID: 6652

NCBI Accession: NP_003095