SPAG8 antibody (C-Term)

Catalog No. ABIN954905

The Rabbit Polyclonal anti-SPAG8 antibody has been validated for WB and EIA. It is suitable to detect SPAG8 in samples from Human.

Quick Overview for SPAG8 antibody (C-Term) (ABIN954905)

Target: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SPAG8 Antibody

Binding Specificity: AA 390-419, C-Term

Specificity: This antibody recognizes Human SPAG8 / SMP1 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 390-419 amino acids from the C-terminal region of Human SPAG8 Genename: SPAG8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPAG8

Target: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Alternative Name: SPAG8 / SMP1

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.Synonyms: BS-84, HSD-1, SMP-1, Sperm membrane protein 1, Sperm-associated antigen 8

Molecular Weight: 44819 Da

Gene ID: 26206

NCBI Accession: NP_001034681