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SNTB2 antibody (Middle Region)
SNTB2
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SNTB2 Antibody
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Target
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SNTB2
(Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))
Binding Specificity
All epitopes for SNTB2 antibodies
AA 216-245, Middle Region
Reactivity
All reactivities for SNTB2 antibodies
Human
Host
All hosts for SNTB2 antibodies
Rabbit
Clonality
All clonalities for SNTB2 antibodies
Polyclonal
Conjugate
All conjugates for SNTB2 antibodies
This SNTB2 antibody is un-conjugated
Application
All applications for SNTB2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects human Syntrophin-3 / SNTB2.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a protein A column,; followed by peptide affinity purification.
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 216-245aa) of human Syntrophin-3 / SNTB2.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SNTB2
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Target
SNTB2
(Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))
Alternative Name
Syntrophin-3 / SNTB2 (SNTB2 Products )
Synonyms
Snt2 antibody, D16S2531E antibody, EST25263 antibody, SNT2B2 antibody, SNT3 antibody, SNTL antibody, syntrophin, basic 2 antibody, syntrophin beta 2 antibody, Sntb2 antibody, SNTB2 antibody
Background
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 basic component 2, Beta-2-syntrophin, SNT2B2, SNT3, SNTL, Syntrophin-like
Gene ID
6645
NCBI Accession
NP_006741
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