TNIP1 antibody (C-Term)

Catalog No. ABIN955281

This anti-TNIP1 antibody is a Rabbit Polyclonal antibody detecting TNIP1 in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for TNIP1 antibody (C-Term) (ABIN955281)

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TNIP1 Antibody

Binding Specificity: AA 454-482, C-Term

Specificity: This antibody detects TNIP1 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Alternative Name: TNIP1

Background: Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.Synonyms: HIV-1 Nef-interacting protein, KIAA0113, NAF1, Nef-associated factor 1, Nip40-1, TNFAIP3-interacting protein 1, VAN, Virion-associated nuclear shuttling protein

Gene ID: 10318

NCBI Accession: NP_006049

Pathways: Activation of Innate immune Response