UQCRB antibody (Middle Region)

Catalog No. ABIN955465

This Rabbit Polyclonal antibody specifically detects UQCRB in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for UQCRB antibody (Middle Region) (ABIN955465)

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UQCRB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-UQCRB Antibody

Binding Specificity: AA 18-47, Middle Region

Specificity: This antibody detects UQCRB (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human UQCRB

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for UQCRB

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Alternative Name: UQCRB

Background: This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.Synonyms: Complex III subunit 7, Complex III subunit VII, Cytochrome b-c1 complex subunit 7, QP-C, UQBP, Ubiquinol-cytochrome c reductase complex 14 kDa protein

Gene ID: 7381

NCBI Accession: NP_001186904