Uroplakin 1B antibody (C-Term)

Catalog No. ABIN955481

The Rabbit Polyclonal anti-Uroplakin 1B antibody is suitable to detect Uroplakin 1B in samples from Human. It has been validated for WB and EIA.

Quick Overview for Uroplakin 1B antibody (C-Term) (ABIN955481)

Target: Uroplakin 1B (UPK1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 159-188, C-Term

Specificity: This antibody detects Uroplakin-1b (UPK1B) (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human UPK1B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: Uroplakin-1b (UPK1B)

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq].Synonyms: TSPAN20, Tetraspanin-20, Tspan-20, UP1b, UPIb, Uroplakin Ib

Gene ID: 7348

NCBI Accession: NP_008883