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WT1 antibody (Middle Region)

WT1 Reactivity: Human IF, WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN955586
  • Target See all WT1 Antibodies
    WT1 (Wilms Tumor 1 (WT1))
    Binding Specificity
    • 33
    • 16
    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 353-383, Middle Region
    Reactivity
    • 149
    • 69
    • 62
    • 17
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 83
    • 65
    • 1
    Rabbit
    Clonality
    • 89
    • 60
    Polyclonal
    Conjugate
    • 75
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WT1 antibody is un-conjugated
    Application
    • 90
    • 82
    • 63
    • 57
    • 33
    • 22
    • 22
    • 14
    • 13
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Wilms tumor protein (Center).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Protein A column followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 353-383 (E361) amino acids from the Central region of human WT1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product WT1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • Target
    WT1 (Wilms Tumor 1 (WT1))
    Alternative Name
    WT1 / Wilms Tumor Protein (WT1 Products)
    Synonyms
    AWT1 antibody, EWS-WT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, WIT-2 antibody, WT33 antibody, CWT1 antibody, WT1 antibody, XWT1a antibody, wt-1 antibody, wt1 antibody, xWT1 antibody, WT-1 antibody, gud antibody, wagr antibody, wt33 antibody, xwt1 antibody, wit-2 antibody, si:ch211-160j6.3 antibody, zgc:152697 antibody, D630046I19Rik antibody, Wt-1 antibody, XWT1b antibody, XeWT1 antibody, Wilms tumor 1 antibody, Wilms tumor 1 S homeolog antibody, wilms tumor 1b antibody, Wilms tumor protein antibody, Wilms tumor 1 homolog antibody, Wilms tumor 1 L homeolog antibody, WT1 antibody, wt1.S antibody, wt1 antibody, wt1b antibody, Wt1 antibody, wt1.L antibody
    Background
    This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].Synonyms: WT33
    Gene ID
    7490
    NCBI Accession
    NP_000369
    Pathways
    Tube Formation
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