CDNF antibody

Catalog No. ABIN956415

This anti-CDNF antibody is a Mouse Monoclonal antibody detecting CDNF in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for CDNF antibody (ABIN956415)

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDNF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7D6

Product Details anti-CDNF Antibody

Specificity: Human, CDNF protein

Purification: purified by protein G affinity chromatography

Immunogen: Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:64 000, WB: 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format

Comment:

Synonym: ARMETL1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml

Buffer: PBS pH 7.4, with 0.1%

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.

Storage: -20 °C

Storage Comment: This product is shipped in non-frozen liquid form in ambient conditions

References for anti-CDNF antibody (ABIN956415)

Galli, Lindholm, Kontturi, Saarma, Urtti, Yliperttula: "Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy." in: Cell transplantation, Vol. 28, Issue 4, pp. 413-424, (2020) (PubMed).

Target Details for CDNF

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Alternative Name: CDNF

Background: CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta

UniProt: Q49AH0