Caveolin-1 antibody (Isoform B)

Catalog No. ABIN965751

Cited in 1 publication. The Rabbit Polyclonal anti-Caveolin-1 antibody (ABIN965751) specifically detects Caveolin-1 in IHC. The antibody is reactive with Great Pond Snail (Lymnaea stagnalis) samples.

Quick Overview for Caveolin-1 antibody (Isoform B) (ABIN965751)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Great Pond Snail (Lymnaea stagnalis)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Caveolin-1 Antibody

Binding Specificity: Isoform B

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Great Pond Snail (Lymnaea stagnalis) Cav1b (voltage-dependent L-type calcium channel alpha-1 subunit isoform b)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-Caveolin-1 antibody (ABIN965751)

Spafford, Munno, Van Nierop, Feng, Jarvis, Gallin, Smit, Zamponi, Syed: "Calcium channel structural determinants of synaptic transmission between identified invertebrate neurons." in: The Journal of biological chemistry, Vol. 278, Issue 6, pp. 4258-67, (2003) (PubMed).

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: Cav1b

Background: Cav1b (voltage-dependent L-type calcium channel alpha-1 subunit isoform b) mediates entry of calcium ions into excitable cells. Cav1b contains multiple Ion_trans domains which are Ion transport protein and also contains transmembrane domain I segment 1,2,3,4,5,6 helix, transmembrane domain II segment 1,2,3,4,5,6 helix, transmembrane domain III segment 1,2,3,4,5,6 helix, transmembrane domain IV segment 1,2,3,4,5,6 helix, which are voltage sensor and transmembrane domain I P-loop, transmembrane domain II P-loop, transmembrane domain III P-loop, which are lining of ion-selective pore, as well as Glu(-) residue of the selectivity filter and III cytoplasmic linker, II-III cytoplasmic linker and III-IV cytoplasmic linker.

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals