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Integrin beta 3 antibody

ITGB3 Reactivity: Human FACS, IHC (fro), IHC (p) Host: Mouse Monoclonal Y2-51 unconjugated
Catalog No. ABIN965812
  • Target See all Integrin beta 3 (ITGB3) Antibodies
    Integrin beta 3 (ITGB3)
    Reactivity
    • 180
    • 92
    • 60
    • 16
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 120
    • 63
    • 11
    • 2
    Mouse
    Clonality
    • 115
    • 79
    Monoclonal
    Conjugate
    • 103
    • 16
    • 11
    • 10
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 3 antibody is un-conjugated
    Application
    • 122
    • 85
    • 53
    • 46
    • 29
    • 28
    • 23
    • 19
    • 15
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Concentrated.
    Immunogen
    Phytohemagglutinin-stimulated Human Mononuclear Cells
    Clone
    Y2-51
    Isotype
    IgG1
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  • Application Notes
    Immunohistochemistry: (Paraffin/Frozen (acetone fixed)) 1:50-1:100, FLOW.
    Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 -1:100 in IHC. When using paraffin-embedded and formalin-fixed tissues, enzymatic predigestion is required. The optimal conditions should be determined by the individual laboratory.
    Comment

    Cellular Localization: Cell Membrane.
    Recommended Positive Control: Lymphoid Tissues

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1 mg/ml.
    Buffer
    20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Ford-Hutchinson: "Regulation of leukotriene biosynthesis." in: Cancer metastasis reviews, Vol. 13, Issue 3-4, pp. 257-67, (1995) (PubMed).

  • Target
    Integrin beta 3 (ITGB3)
    Alternative Name
    CD61, Platelet Glycoprotein IIIa (ITGB3 Products)
    Background
    This antibody reacts with platelet glycoprotein IIIa, a 110 kD glycoprotein present on human platelets and megakaryocytic progenitors. This antibody reacts with platelets, megakaryocytes, megakaryoblasts, endothelium, and osteoclasts.
    Gene ID
    3690
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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