Cytokeratin 19 antibody (AA 80-400)

Catalog No. ABIN965959

This Mouse Monoclonal antibody specifically detects Cytokeratin 19 in WB, IHC and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for Cytokeratin 19 antibody (AA 80-400) (ABIN965959)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4F12G9

Product Details anti-Cytokeratin 19 Antibody

Binding Specificity: AA 80-400

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of Cytokeratin 19 (aa80-400) expressed in E. Coli strain.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Cytokeratin 19 antibody (ABIN965959)

Flanagan, Pineda, Knapp, De Las Morenas, Lee, Braverman: "Expression of cytokeratin 19 in the diagnosis of thyroid papillary carcinoma by quantitative polymerase chain reaction." in: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Vol. 14, Issue 2, pp. 168-74, (2008) (PubMed).

Mizuguchi, Nishiyama, Iwata, Nishida, Izumi, Tsukioka, Inoue, Uenishi, Wakasa, Suehiro: "Serum Sialyl Lewis x and cytokeratin 19 fragment as predictive factors for recurrence in patients with stage I non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 58, Issue 3, pp. 369-75, (2007) (PubMed).

Target Details for Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Alternative Name: Cytokeratin 19

Background: Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
Synonyms: CK19, K1CS, MGC15366, KRT19

Molecular Weight: 44kDa

Gene ID: 3880