Decorin antibody (Isoform d)

Catalog No. ABIN965978

The Rabbit Polyclonal anti-Decorin antibody has been validated for IHC. It is suitable to detect Decorin in samples from Human. There is 1 publication available.

Quick Overview for Decorin antibody (Isoform d) (ABIN965978)

Target: Decorin (DCN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Decorin Antibody

Binding Specificity: Isoform d

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human DCN (decorin isoform d precursor) Or dermatan sulphate proteoglycans II, bone proteoglycan II, proteoglycan core protein, small leucinerich protein 1B.

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Decorin antibody (ABIN965978)

Al-Mansi, Abdel: "Recovery of nickel oxide from spent catalyst." in: Waste management (New York, N.Y.), Vol. 22, Issue 1, pp. 85-90, (2002) (PubMed).

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: DCN

Background: The DCN(decorin isoform d) is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils,and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. The decorin supports adhesion and activation of human platelets. The decorin can disrupt glucose and TGFbeta/Smad-dependent transcription in mesangial cells through a mechanism that involves an increase in Ca(2+) signalling, the activation of Ca(2+)/calmodulin-dependent protein kinase II and phosphorylation of Smad2

Pathways: Glycosaminoglycan Metabolic Process