Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

Catalog No. ABIN965991

Cited in 1 publication. The Rabbit Polyclonal anti-Der1-Like Domain Family, Member 2 antibody (ABIN965991) specifically detects Der1-Like Domain Family, Member 2 in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody (ABIN965991)

Target: Der1-Like Domain Family, Member 2 (DERL2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Product Details

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, (2001) (PubMed).

Target Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Alternative Name: DERL2

Background: DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Pathways: ER-Nucleus Signaling, Feeding Behaviour