FnbA (C-Term) antibody

Catalog No. ABIN966158

There are 2+ publications for this product available. The Rabbit Polyclonal anti-FnbA antibody is suitable to detect FnbA in samples from Staphylococcus aureus. It has been validated for IHC.

Quick Overview for FnbA (C-Term) antibody (ABIN966158)

Target: FnbA

Reactivity: Staphylococcus aureus

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC)

Product Details

Binding Specificity: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Bacteria: Staphylococcus aureus FnbA (Fibronectin-binding protein A)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References

Diep, Gill, Chang, Phan, Chen, Davidson, Lin, Lin, Carleton, Mongodin, Sensabaugh, Perdreau-Remington: "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." in: Lancet, Vol. 367, Issue 9512, pp. 731-9, (2006) (PubMed).

Gill, Fouts, Archer, Mongodin, Deboy, Ravel, Paulsen, Kolonay, Brinkac, Beanan, Dodson, Daugherty, Madupu, Angiuoli, Durkin, Haft, Vamathevan, Khouri, Utterback, Lee, Dimitrov, Jiang, Qin, Weidman, Tran, Kang, Hance, Nelson, Fraser: "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." in: Journal of bacteriology, Vol. 187, Issue 7, pp. 2426-38, (2005) (PubMed).

Target Details

Target: FnbA

Background: FnbA (Fibronectin-binding protein A) promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin. This confers to S.aureus the ability to invade endothelial cells. FnbA (Fibronectin-binding protein A) promotes adherence to and aggregation of activated platelets. FnbA (Fibronectin-binding protein A) is secreted, cell wall Peptidoglycan-anchor.