GCNT3 antibody (N-Term)

Catalog No. ABIN966194

There are 3+ publications for this product available. The Rabbit Polyclonal anti-GCNT3 antibody is suitable to detect GCNT3 in samples from Human. It has been validated for IHC.

Quick Overview for GCNT3 antibody (N-Term) (ABIN966194)

Target: GCNT3 (Glucosaminyl (N-Acetyl) Transferase 3, Mucin Type (GCNT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCNT3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-GCNT3 Antibody

Binding Specificity: N-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human GCNT3 (Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-Nacetylglucosaminyltransferase 3)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-GCNT3 antibody (ABIN966194)

Tözüm, Türkyilmaz, Yamalik, Tümer, Kilinç, Kilinç, Karabulut, Eratalay: "The effect of delayed versus early loading on nitric oxide metabolism around dental implants: an 18-month comparative follow-up study." in: The International journal of oral & maxillofacial implants, Vol. 22, Issue 1, pp. 53-62, (2007) (PubMed).

Yeh, Ong, Fukuda: "Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches." in: The Journal of biological chemistry, Vol. 274, Issue 5, pp. 3215-21, (1999) (PubMed).

Schwientek, Nomoto, Levery, Merkx, van Kessel, Bennett, Hollingsworth, Clausen: "Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4." in: The Journal of biological chemistry, Vol. 274, Issue 8, pp. 4504-12, (1999) (PubMed).

Target Details for GCNT3

Target: GCNT3 (Glucosaminyl (N-Acetyl) Transferase 3, Mucin Type (GCNT3))

Alternative Name: GCNT3

Background: GCNT3 (Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-Nacetylglucosaminyltransferase 3) is a glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. GCNT3 mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. GCNT3 has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. GCNT3 belongs to the glycosyltransferase 14 family.
Synonyms: C2/4GnT (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase)

Pathways: Production of Molecular Mediator of Immune Response