HPS1 antibody

Catalog No. ABIN966298

This Mouse Monoclonal antibody specifically detects HPS1 in WB and ELISA. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for HPS1 antibody (ABIN966298)

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5G12G2

Product Details anti-HPS1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of HPS1 expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-HPS1 antibody (ABIN966298)

Kobashi, Yoshida, Miyashita, Niki, Matsushima: "Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene." in: Internal medicine (Tokyo, Japan), Vol. 44, Issue 6, pp. 616-21, (2005) (PubMed).

Nazarian, Falcón-Pérez, DellAngelica: "Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8770-5, (2003) (PubMed).

Target Details for HPS1

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Alternative Name: HPS1

Background: Hermansky-Pudlak syndrome 1. This protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene, the full-length sequences of some of these have not been determined yet.
Synonyms: HPS, MGC5277, HPS1

Gene ID: 3257