IL-8 antibody

Catalog No. ABIN966396

This anti-IL-8 antibody is a Monoclonal antibody detecting IL-8 in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for IL-8 antibody (ABIN966396)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This IL-8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-8 Antibody

Specificity: Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1 kappa

Application Details

Application Notes: Dilution: Western Blot: 1:500-1,000
ELISA: 1,000-2,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-IL-8 antibody (ABIN966396)

Baggiolini, Clark-Lewis: "Interleukin-8, a chemotactic and inflammatory cytokine." in: FEBS letters, Vol. 307, Issue 1, pp. 97-101, (1992) (PubMed).

Mukaida, Shiroo, Matsushima: "Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 143, Issue 4, pp. 1366-71, (1989) (PubMed).

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8

Background: Interleukin-8 (IL-8)is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

Gene ID: 3576

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy