KLF4 antibody

Catalog No. ABIN966457

This Mouse Monoclonal antibody specifically detects KLF4 in WB, IHC and IF. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for KLF4 antibody (ABIN966457)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1E6

Product Details anti-KLF4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLF4 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-KLF4 antibody (ABIN966457)

Xu, Lü, Xu, Gu, Fang, Huang, Lai: "Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence." in: Journal of cancer research and clinical oncology, Vol. 134, Issue 8, pp. 891-8, (2008) (PubMed).

Barbe, Lundberg, Oksvold, Stenius, Lewin, Björling, Asplund, Pontén, Brismar, Uhlén, Andersson-Svahn: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, (2008) (PubMed).

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background: Kruppel-like factor 4 (gut),endothelial Kruppel-like zinc finger protein. May act as a transcriptional activator. Binds the CACCC core sequence. May be involved in the differentiation of epithelial cells and may also function in the development of the skeleton and kidney. KLF4 is highly expressed in the epithelial cells of the skin and the gastrointestinal tract.
Synonyms: EZF, GKLF, KLF4

Molecular Weight: 54kDa

Gene ID: 9315

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance