Neurogenin 3 antibody

Catalog No. ABIN966645

Cited in 2+ publications. The Mouse Monoclonal anti-Neurogenin 3 antibody (Clone 6G2) (ABIN966645) specifically detects Neurogenin 3 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Neurogenin 3 antibody (ABIN966645)

Target: Neurogenin 3 (NEUROG3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neurogenin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6G2

Product Details anti-Neurogenin 3 Antibody

Purification: Liquid

Immunogen: Purified recombinant fragment of human Neurogenin-3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Neurogenin 3 antibody (ABIN966645)

Heremans, Van De Casteele, int Veld, Gradwohl, Serup, Madsen, Pipeleers, Heimberg: "Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3." in: The Journal of cell biology, Vol. 159, Issue 2, pp. 303-12, (2002) (PubMed).

Gradwohl, Dierich, LeMeur, Guillemot: "neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 4, pp. 1607-11, (2000) (PubMed).

Target Details for Neurogenin 3

Target: Neurogenin 3 (NEUROG3)

Alternative Name: Neurogenin-3

Background: Neurogenin-3 (NEUROG3), also known as NGN3, it is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm.
Synonyms: ngn3, Atoh5, Math4B, bHLHa7, NEUROG3

Molecular Weight: 23kDa

Gene ID: 50674