TGFA antibody (C-Term)

Catalog No. ABIN967168

This Polyclonal antibody specifically detects TGFA in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for TGFA antibody (C-Term) (ABIN967168)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TGFA Antibody

Binding Specificity: AA 73-90, C-Term

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human TGF (73-90 aa), different from the mouse sequence by one amino acid.

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

References for anti-TGFA antibody (ABIN967168)

Fallon, Reid, Kinyamu, Opole, Opole, Baratta, Korc, Endo, Duong, Nguyen, Karkehabadhi, Twardzik, Patel, Loughlin: "In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 26, pp. 14686-91, (2001) (PubMed).

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: TGFalpha

Background: Transforming growth factor alpha (TGF-) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGF stimulates neural cell proliferation in the adult injured brain. TGF was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway