VASP antibody

Catalog No. ABIN967239

Cited in 5+ publications. The Rabbit Polyclonal anti-VASP antibody (ABIN967239) specifically detects VASP in IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for VASP antibody (ABIN967239)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VASP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-VASP Antibody

Specificity: VASP (Ab-157) antibody detects endogenous levels of total VASP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human VASP around the phosphorylation site of serine 157 (R-V-SP-N-A).

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-VASP antibody (ABIN967239)

Millard, Bompard, Heung, Dafforn, Scott, Machesky, Fütterer: "Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53." in: The EMBO journal, Vol. 24, Issue 2, pp. 240-50, (2005) (PubMed).

Kühnel, Jarchau, Wolf, Schlichting, Walter, Wittinghofer, Strelkov: "The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 49, pp. 17027-32, (2004) (PubMed).

Zhao, Jiang, Kroll, Huber: "A proline-rich protein binds to the localization element of Xenopus Vg1 mRNA and to ligands involved in actin polymerization." in: The EMBO journal, Vol. 20, Issue 9, pp. 2315-25, (2001) (PubMed).

Ramesh, Antón, Hartwig, Geha: "WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14671-6, (1998) (PubMed).

Haffner, Jarchau, Reinhard, Hoppe, Lohmann, Walter: "Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP." in: The EMBO journal, Vol. 14, Issue 1, pp. 19-27, (1995) (PubMed).

Target Details for VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Alternative Name: VASP

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation