VEGFR2/CD309 antibody
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- Target See all VEGFR2/CD309 (VEGFR2) Antibodies
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VEGFR2/CD309 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- VEGFR2 (Ab-1175) antibody detects endogenous levels of total VEGFR2 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V).
- Top Product
- Discover our top product VEGFR2 Primary Antibody
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- Application Notes
- IHC: 1:50-1:100.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, (2004) (PubMed).
: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, (2001) (PubMed).
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Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, (2004) (PubMed).
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- Target
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- Alternative Name
- VEGFR2 (VEGFR2 Products)
- Pathways
- RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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