ABL2 antibody

Catalog No. ABIN968943

This anti-ABL2 antibody is a Mouse Monoclonal antibody detecting ABL2 in ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for ABL2 antibody (ABIN968943)

Target: ABL2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABL2 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 1H1B11

Product Details anti-ABL2 Antibody

Purpose: ABL2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of ABL2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ABL2 antibody (ABIN968943)

Scheijen, Griffin: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).

Iijima, Ito, Oikawa, Eguchi, Eguchi-Ishimae, Kamada, Kishi, Asano, Sakaki, Sato: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." in: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).

Target Details for ABL2

Target: ABL2

Alternative Name: ABL2

Background: ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

Gene ID: 27

UniProt: P42684