CD1a antibody

Catalog No. ABIN969017

The Mouse Monoclonal anti-CD1a antibody has been validated for IHC, WB, ELISA and ICC. It is suitable to detect CD1a in samples from Human. There are 2+ publications available.

Quick Overview for CD1a antibody (ABIN969017)

Target: CD1a

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1a antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 7A7

Product Details anti-CD1a Antibody

Purpose: CD1A Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD1A expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD1a antibody (ABIN969017)

Adachi, Horie, Kitamura, Nakamura, Taniguchi, Miwa, Fujioka, Nishimura, Hayashi: "CD1a expression in PEComas." in: Pathology international, Vol. 58, Issue 3, pp. 169-73, (2008) (PubMed).

Kuijf, Geleijns, Ennaji, van Rijs, van Doorn, Jacobs: "Susceptibility to Guillain-Barré syndrome is not associated with CD1A and CD1E gene polymorphisms." in: Journal of neuroimmunology, Vol. 205, Issue 1-2, pp. 110-2, (2008) (PubMed).

Target Details for CD1a

Target: CD1a

Alternative Name: CD1A

Background: CD1a is a non polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin. CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells. CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X. Tissue specificity: Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.

Molecular Weight: 37 kDa

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process