CD37 antibody

Catalog No. ABIN969022

This Mouse Monoclonal antibody specifically detects CD37 in ELISA and ICC. It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for CD37 antibody (ABIN969022)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD37 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 2B8

Product Details anti-CD37 Antibody

Purpose: CD37 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of CD37 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD37 antibody (ABIN969022)

Wehkamp, Wang, Kübler, Nuding, Gregorieff, Schnabel, Kays, Fellermann, Burk, Schwab, Clevers, Bevins, Stange: "The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 5, pp. 3109-18, (2007) (PubMed).

van Spriel, Puls, Sofi, Pouniotis, Hochrein, Orinska, Knobeloch, Plebanski, Wright: "A regulatory role for CD37 in T cell proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 5, pp. 2953-61, (2004) (PubMed).

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 31.7 kDa

Gene ID: 951

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response